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Work by this group has shown that adult neural stem cells upon stimulation with growth factors PDGF give rise to glioma-like masses next to the SVZ. Age doesn't matter the older romos better!
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He and colleagues then identifies in the adult mammalian brain subventricular zone SVZ a large population of neuronal precursors; demonstrates long range migration of wex neurons from the SVZ to the olfactory bulb; Identified the mechanism of cell translocation as chain migration and uncovered an extensive network of pathways for chain migration in the adult mammalian brain.
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Fernando Nottebohm demonstrated the migration of young neurons in adult song birds; showed that long projection neurons continue to form in the high vocal center of adult songbirds, and horny as hell, the Alvarez-Buylla laboratory discovers that adult neural stem cells are heterogeneous and that different types of neurons in the olfactory bulb are derived from specific locations in the SVZ!
His laboratory shows that these cells in the SVZ give rise to transit amplifying cells Type C cells that generate both neurons and oligodendrocytes during postnatal life. Put FWB in the subject line. The Alvarez-Buylla laboratory identified the neural stem cells in the adult mammalian brain SVZ and hippocampus?
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